Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 9/20 | 0.45 |
| ▸ | CLK1 | P49759 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695448 | 0.88 | MGLL (0.43) | ALDH1A1GAAHRH4L3MBTL1CYP11B1 | |
| SCHEMBL20695161 | 0.88 | LMNA (0.43) | CLK1ALDH1A1GAAHRH4L3MBTL1 | |
| SCHEMBL20695172 | 0.86 | HRH4 (0.52) | ALDH1A1HRH4L3MBTL1CA2 | |
| SCHEMBL20695487 | 0.85 | CHRNA7 (0.44) | CLK1ALDH1A1GAAHRH4L3MBTL1 | |
| SCHEMBL20695465 | 0.85 | CLK1 (0.46) | DYRK1ADYRK1BCLK1ALDH1A1 | |
| SCHEMBL20695141 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GAAHRH4 | |
| SCHEMBL20695242 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAHRH4L3MBTL1MGLL | |
| SCHEMBL20695359 | 0.82 | CHRNA7 (0.39) | DYRK1ADYRK1BCLK1ALDH1A1GAA | |
| SCHEMBL20695239 | 0.81 | CHRNA7 (0.41) | HRH4L3MBTL1MGLL | |
| SCHEMBL20695368 | 0.81 | MGLL (0.45) | CLK1ALDH1A1HRH4L3MBTL1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438109-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | disclosed |