Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | AOC2 | O75106 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20709044 | 0.84 | MAOB (0.69) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL20005678 | 0.84 | MAOB (0.69) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL12477808 | 0.74 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL246234 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4E | |
| SCHEMBL9468836 | 0.73 | AGXT (0.54) | MAOBAOC2MAOADAOLMNA | |
| SCHEMBL27325034 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL29950923 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16767511 | 0.72 | AOC3 (0.77) | MAOBAOC2MAOADAOALDH1A1 | |
| SCHEMBL16766763 | 0.72 | AOC3 (0.77) | MAOBAOC2MAOADAOALDH1A1 | |
| SCHEMBL349060 | 0.72 | ALOX15 (0.61) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438087-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-02-06 | — | — | EP | disclosed |