Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477808 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL20233419 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL5696003 | 0.81 | GPR174 (0.50) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL29952429 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL2555934 | 0.80 | MAOA (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL20196947 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL349060 | 0.77 | ALOX15 (0.61) | ALDH1A1MAPTSMN1; SMN2KMT2ATSHR | |
| SCHEMBL9856084 | 0.76 | LTA4H (0.45) | ALDH1A1MAPTHPGDLMNAKMT2A | |
| SCHEMBL5593929 | 0.76 | ATF4 (0.50) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL29956255 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |