Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20710809 | 0.90 | LTA4H (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20710788 | 0.87 | TRPM8 (0.40) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL20710734 | 0.87 | LTA4H (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL20710857 | 0.86 | MEN1 (0.35) | TP53 | |
| SCHEMBL20710834 | 0.83 | LTA4H (0.47) | RAB9ASMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL20710833 | 0.81 | DRD2 (0.40) | SMN1; SMN2 | |
| SCHEMBL2931114 | 0.80 | TP53 (0.44) | KDM4EALDH1A1TP53IDO1AGXT | |
| SCHEMBL20710794 | 0.80 | MAPT (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20710775 | 0.79 | MAOB (0.36) | TP53PPARGPPARAIDO1 | |
| SCHEMBL20710813 | 0.79 | KMT2A (0.36) | SMN1; SMN2HPGDKDM4EALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028391-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2019-02-07 | — | — | WO | disclosed |