Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20710750 | 0.89 | APP (0.36) | TP53ALDH1A1MAPK1GAAKMT2A | |
| SCHEMBL443626 | 0.89 | LTA4H (0.43) | LTA4HTP53TSHRRELALMNA | |
| SCHEMBL385592 | 0.85 | LTA4H (0.43) | LTA4HTP53TSHRRELALMNA | |
| SCHEMBL20710748 | 0.84 | CA4 (0.52) | LTA4HALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL20710810 | 0.84 | LTA4H (0.41) | LTA4HTSHRRELAKMT2AMEN1 | |
| SCHEMBL20710847 | 0.84 | RAB9A (0.41) | LTA4HTP53ALDH1A1MAPK1GAA | |
| SCHEMBL11557684 | 0.83 | LTA4H (0.42) | LTA4HTP53TSHRRELALMNA | |
| SCHEMBL20710763 | 0.82 | MAOA (0.48) | LTA4HTP53ALDH1A1TDP1MAPK1 | |
| SCHEMBL11675392 | 0.81 | LTA4H (0.41) | LTA4HTP53TSHRRELALMNA | |
| SCHEMBL28878265 | 0.80 | LTA4H (0.37) | LTA4HTP53RELAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028391-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2019-02-07 | — | — | WO | disclosed |