Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571239 | 0.86 | PDK1 (0.70) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL4608458 | 0.86 | PDK1 (0.70) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL11358347 | 0.85 | CXCR1 (0.58) | ALDH1A1HTTMEN1KMT2AHPGD | |
| SCHEMBL10420241 | 0.84 | MAPT (0.57) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL3271853 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HTTMEN1KMT2AHPGD | |
| SCHEMBL4490833 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HTTMEN1KMT2AHPGD | |
| SCHEMBL30168131 | 0.83 | HTT (0.74) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL1285405 | 0.83 | HTT (0.74) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL31261387 | 0.82 | MAPT (0.59) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL4966134 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HTTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906537-B2 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2011-03-15 | — | — | US | disclosed |
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2006-08-17 | — | — | US | disclosed |
| US-20030229072-A1 | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binning agents | BULLOCK WILLIAM H (US) | 2003-12-11 | — | — | US | disclosed |
| EP-1317456-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020526-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | ABCB1, UGT2B7, CYP2D6 | ALDH1A1 112/4885HTT 3204/4885MEN1 1715/4885 |
| US-20030229072-A1 | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binning agents | PGR, PGRMC1, PGRMC2 | ALDH1A1 4704/4885HTT 4428/4885MEN1 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.