Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL25387939 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL11218475 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL29270383 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL29270380 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL11588624 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL29057535 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL28200793 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL28883597 | 0.93 | ALDH1A1 (0.61) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL7633779 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15CA2CA4 | |
| Styrene SCHEMBL1402211 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRALOX15CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119673957-A | Positive electrode plate, secondary battery and electronic device | 宁德新能源科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118325519-A | Conductive adhesive and battery comprising same | 浙江冠宇电池有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117463497-A | Ore dressing device and method for fine-fraction tin ore | 广西华锡有色金属股份有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-116213129-A | Collecting agent for sorting garnet and ilmenite and floatation process thereof | 山东域潇锆钛矿业股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-113119350-B | Method for mineralizing, enriching and separating environmental micro-nano plastic pollutants | 郑州大学 | 2023-03-24 | — | — | CN | claimed |
| CN-114656188-B | Composite gypsum retarder and preparation method thereof | 欣格瑞（山东）环境科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115487942-A | Flotation silicon reduction treatment method for high-silicon titanium slag | 四川顺应动力电池材料有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-114316120-B | Coated propping tracer containing rare earth metal elements and preparation method and application thereof | 陕西科技大学 | 2022-12-09 | — | — | CN | claimed |
| CN-113560030-B | Beneficiation method of vanadium-titanium magnetite concentrate | 中南大学 | 2022-11-08 | — | — | CN | claimed |
| CN-115160500-A | Multi-response controllable crosslinking degradation gel particle temporary plugging agent and preparation method and application thereof | 中国地质大学（武汉） | 2022-10-11 | — | — | CN | claimed |
| CN-1433468-A | Surface modified supporting materials for binding biological materials, method for the production and use thereof | INVITEK GMBH (DE) | 2003-07-30 | — | — | CN | claimed |
| EP-1274791-A1 | SALT SENSITIVE AQUEOUS EMULSIONS | National Starch & Chemical Company (US) | 2003-01-15 | — | — | EP | claimed |
| EP-0592989-B1 | Process of the selective and quantitative removal or preparation of tumor necrosis factor (TNF) and lipopolysaccharides (LPS) of aqueous solutions | BRAUN MELSUNGEN AG (DE) | 2002-05-08 | — | — | EP | claimed |
| US-20010049025-A1 | Multilayer films having flame retardant layers | 3M INNOVATIVE PROPERTIES COMPANY | 2001-12-06 | — | — | US | claimed |
| WO-2001074941-A1 | SALT SENSITIVE AQUEOUS EMULSIONS | NATIONAL STARCH & CHEMICAL COMPANY (US) | 2001-10-11 | — | — | WO | claimed |
| US-6103145-A | ACID CONTAINING POLYMERS AND BASIC POLYMERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2000-08-15 | — | — | US | claimed |
| WO-2000016811-A2 | MRI CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | claimed |
| US-6010645-A | FORM A POLYACID AND CONJUGATED POLYMER | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2000-01-04 | — | — | US | claimed |
| US-5733949-A | Antimicrobial adhesive composition for dental uses | KURARAY CO., LTD. (JP) | 1998-03-31 | — | — | US | claimed |
| US-5403917-A | Process for the quantitative selective removal or preparative isolation of tumour necrosis factor (TNF) or/and lipopolysaccharides (LPS) from aqueous liquids | B. BRAUN MELSUNGEN, AG (DE) | 1995-04-04 | — | — | US | claimed |