Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714819 | 0.82 | MAPT (0.50) | ICMTHTTMAPTABL1CYP3A4 | |
| SCHEMBL18263394 | 0.82 | STK17A (0.50) | ICMTALDH1A1HTTMAPTABL1 | |
| SCHEMBL10779665 | 0.81 | ALDH1A1 (0.54) | ICMTALDH1A1HTTMAPTABL1 | |
| SCHEMBL20714654 | 0.79 | RAPGEF4 (0.45) | ICMTALDH1A1MAPTABL1CYP1A2 | |
| SCHEMBL20714856 | 0.79 | MAPT (0.43) | ALDH1A1HTTMAPTCYP1A2CYP3A4 | |
| SCHEMBL1800169 | 0.79 | ALDH1A1 (0.46) | ICMTALDH1A1HTTMAPTABL1 | |
| SCHEMBL9782316 | 0.78 | NPC1 (0.42) | ICMTALDH1A1HTTMAPTABL1 | |
| SCHEMBL20714815 | 0.78 | ABL1 (0.61) | ALDH1A1HTTMAPTABL1CYP1A2 | |
| SCHEMBL20714669 | 0.77 | MAPT (0.43) | ALDH1A1MAPTABL1CYP3A4CYP2C9 | |
| SCHEMBL18300960 | 0.76 | RAPGEF4 (0.40) | ICMTALDH1A1HTTMAPTABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |