SCHEMBL20715741

SCHEMBL20715741

CNCCCC[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CNC(C)=O)NC(=O)[C@@H](N)Cc1ccc(Cl)cc1)C(=O)NC(C(=O)NCC(=O)N[C@@H](C=O)Cc1ccc(O)cc1)C(C)O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 18/20 0.49
▸ OPRM1 P35372 11/20 0.49
▸ OPRK1 P41145 3/20 0.49
▸ CCKAR P32238 3/20 0.40
▸ CCKBR P32239 3/20 0.40
▸ NPY1R P25929 1/20 0.39
▸ NPY2R P49146 1/20 0.39
▸ NPY4R P50391 1/20 0.39
▸ NPY5R Q15761 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24324761 0.85 OPRM1 (0.52) OPRD1OPRM1OPRK1NPY1RNPY2R
SCHEMBL19234708 0.80 OPRD1 (0.51) OPRD1OPRM1OPRK1NPY1RNPY2R
SCHEMBL20715581 0.79 OPRM1 (0.51) OPRD1OPRM1OPRK1NPY1RNPY2R
SCHEMBL24340683 0.77 OPRM1 (0.43) OPRD1OPRM1OPRK1
SCHEMBL19234984 0.75 OPRM1 (0.50) OPRD1OPRM1OPRK1NPY1RNPY2R
SCHEMBL26873736 0.74 OPRM1 (0.48) OPRD1OPRM1OPRK1
SCHEMBL31243914 0.72 OPRD1 (0.63) OPRD1OPRM1OPRK1
SCHEMBL19234992 0.71 NPY4R (0.53) OPRD1OPRM1OPRK1NPY1RNPY2R
SCHEMBL31243949 0.71 OPRD1 (0.61) OPRD1OPRM1OPRK1
SCHEMBL24340659 0.71 NPY5R (0.46) NPY1RNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 — — US disclosed
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2019-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 OPRD1 1915/4885OPRM1 1027/4885OPRK1 1042/4885
US-20190040102-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 OPRD1 1915/4885OPRM1 1027/4885OPRK1 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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