SCHEMBL20715965

SCHEMBL20715965

CC(=O)C(Cc1cccc(CC(C)(C)C(=O)O)c1)(Cc1cccc(CC(C)(C)C(=O)O)c1)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP1A2 P05177 3/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 3/20 0.37
POLB P06746 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
EGFR P00533 1/20 0.37
FYN P06241 1/20 0.37
GAA P10253 1/20 0.37
APEX1 P27695 1/20 0.37
ADRA1A P35348 1/20 0.37
PTGS2 P35354 1/20 0.37
MTOR P42345 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20715967 0.94 ALDH1A1 (0.37) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL14740848 0.89 CYP1A2 (0.45) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL20715971 0.88 HPGD (0.36) ALDH1A1KDM4ECYP3A4HPGDL3MBTL1
SCHEMBL29368049 0.88 CYP1A2 (0.44) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL19182697 0.86 SMN1; SMN2 (0.46) ALDH1A1CYP1A2CYP2C19CYP3A4RECQL
SCHEMBL20715963 0.83 ALDH1A1 (0.42) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL25633562 0.83 BCL2 (0.46) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL20715968 0.83 CYP1A2 (0.41) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL20715972 0.81 SLC22A12 (0.36) ALDH1A1CYP1A2CYP2C19KDM4EPOLB
SCHEMBL20715653 0.80 TRPA1 (0.45) ALDH1A1CYP1A2CYP2C19KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019025575-A1 PROCESSES FOR PREPARING COMPLEXES COMPRISING RHODIUM(II) AND CARBOXYLATE LIGANDS STOCKHOLM UNIVERSITY HOLDING AB (SE) 2019-02-07 WO disclosed
WO-2017129991-A2 PROCESSES FOR PREPARING STERICALLY CONGESTED DICARBOXYLIC ACID LIGANDS AND PRODUCTS THEREOF STOCKHOLM UNIVERSITY HOLDING AB (SE) 2017-08-03 WO disclosed