SCHEMBL14740848

SCHEMBL14740848

CC(C)(Cc1cccc(CC(C)(C)C(=O)O)c1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 3/20 0.43
POLB P06746 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
BLM P54132 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
EGFR P00533 1/20 0.43
FYN P06241 1/20 0.43
GAA P10253 1/20 0.43
APEX1 P27695 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368049 0.98 CYP1A2 (0.44) CYP1A2CYP2C19SMN1; SMN2HIF1AKDM4E
SCHEMBL20715968 0.93 CYP1A2 (0.41) CYP1A2CYP2C19SMN1; SMN2HIF1AKDM4E
SCHEMBL25633562 0.93 BCL2 (0.46) CYP1A2CYP2C19SMN1; SMN2HIF1AKDM4E
SCHEMBL20715653 0.89 TRPA1 (0.45) CYP1A2CYP2C19SMN1; SMN2HIF1AKDM4E
SCHEMBL20715965 0.89 ALDH1A1 (0.41) CYP1A2CYP2C19SMN1; SMN2HIF1AKDM4E
SCHEMBL692554 0.89 CTBP2 (0.49) KDM4EPOLBALDH1A1CYP3A4HPGD
SCHEMBL14611102 0.88 ALDH1A1 (0.46) CYP1A2CYP2C19ALDH1A1MEN1GAA
SCHEMBL19776008 0.88 PPARA (0.43) CYP1A2CYP2C19SMN1; SMN2KDM4EPOLB
SCHEMBL23123860 0.87 RIPK1 (0.52) EGFRL3MBTL1RIPK1TAAR1
SCHEMBL21313898 0.87 RIPK1 (0.52) SMN1; SMN2ALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096300-A1 NOVEL METHODS FOR THE PREPARATION OF 3-AZABICYLCO[3.1,0]HEXANE-6-CARBOXAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2025-05-08 WO claimed
EP-3805337-B1 INK COMPOSITIONS AND QUANTUM DOT POLYMER COMPOSITE PATTERN PREPARED FROM THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-08-09 EP claimed
US-11248139-B2 Ink compositions and quantum dot polymer composite pattern prepared from the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-15 US claimed
EP-3805337-A1 INK COMPOSITIONS AND QUANTUM DOT POLYMER COMPOSITE PATTERN PREPARED FROM THE SAME Samsung Display Co., Ltd. (KR) 2021-04-14 EP claimed
US-20210102084-A1 INK COMPOSITIONS AND QUANTUM DOT POLYMER COMPOSITE PATTERN PREPARED FROM THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-08 US claimed
US-9783512-B2 Bicyclic methylene aziridines and reactions thereof WISCONSIN ALUMI RESEARCH FOUNDATION (US) 2017-10-10 US claimed
US-20160075668-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION 2016-03-17 US claimed
US-9221842-B2 Bicyclic methylene aziridines and reactions thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-12-29 US claimed
US-20130079511-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-03-28 US claimed
EP-4719393-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2026-04-08 EP disclosed
EP-4635570-A2 PYRIMIDIN-2-YLAMINO-1H-PYRAZOLS AS LRRK2 INHIBITORS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS Denali Therapeutics Inc. (US) 2025-10-22 EP disclosed
US-12358896-B2 LRRK2 inhibitors and methods of making and using thereof DENALI THERAPEUTICS INC. (US) 2025-07-15 US disclosed
WO-2025096300-A1 NOVEL METHODS FOR THE PREPARATION OF 3-AZABICYLCO[3.1,0]HEXANE-6-CARBOXAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2025-05-08 WO disclosed
EP-3998261-B1 PYRIMIDIN-2-YLAMINO-1H-PYRAZOLS AS LRRK2 INHIBITORS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS DENALI THERAPEUTICS INC (US) 2025-05-07 EP disclosed
US-20160340305-A1 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-11-24 US disclosed
US-20160075668-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION 2016-03-17 US disclosed
US-9221842-B2 Bicyclic methylene aziridines and reactions thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-12-29 US disclosed
WO-2015103505-A2 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS ESS DANIEL HALSELL (US) 2015-07-09 WO disclosed
US-20130079511-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-03-28 US disclosed
WO-2013033245-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340305-A1 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS AAAS, NISCH, HNMT CYP1A2 38/4885CYP2C19 93/4885SMN1; SMN2 3621/4885
US-20160075668-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF AAAS, CYCS, AOC2 CYP1A2 59/4885CYP2C19 39/4885SMN1; SMN2 3154/4885
US-12358896-B2 LRRK2 inhibitors and methods of making and using thereof LRRK2, PARK7, GSK3B CYP1A2 4568/4885CYP2C19 3095/4885SMN1; SMN2 174/4885
US-20130079511-A1 BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF AAAS, CYCS, AOC2 CYP1A2 59/4885CYP2C19 39/4885SMN1; SMN2 3154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.