Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20716310 | 0.85 | NPFFR2 (0.41) | NPFFR2KDRSLC6A3RAPGEF3RAPGEF4 | |
| SCHEMBL22687589 | 0.79 | LMNA (0.43) | NPFFR2KDRPDK1RAPGEF3RAPGEF4 | |
| SCHEMBL20716457 | 0.79 | LMNA (0.43) | NPFFR2KDRPDK1RAPGEF3RAPGEF4 | |
| SCHEMBL20716398 | 0.73 | HTT (0.40) | — | |
| SCHEMBL20702662 | 0.72 | KDR (0.50) | NPFFR2KDRPDK1SLC6A3HTR3E | |
| SCHEMBL20716132 | 0.71 | TAS1R3 (0.39) | PPARA | |
| SCHEMBL20714552 | 0.70 | APP (0.43) | ALDH1A1 | |
| SCHEMBL16957216 | 0.69 | NPFFR2 (0.55) | NPFFR2KDRPDK1SLC6A3HTR3E | |
| SCHEMBL16795634 | 0.69 | NPFFR2 (0.48) | NPFFR2KDRPDK1SLC6A3HTR3E | |
| SCHEMBL10656533 | 0.68 | KDR (0.56) | NPFFR2KDRPDK1SLC6A3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025562-A1 | DIHYDROOXADIAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |