Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 5/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.37 |
| ▸ | PARP1 | P09874 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19135976 | 0.86 | NPSR1 (0.46) | GSK3BNPSR1PPOXWEE1CHEK1 | |
| SCHEMBL7598198 | 0.80 | PARP1 (0.41) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL29541 | 0.80 | PARP1 (0.50) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL30606639 | 0.80 | PARP1 (0.50) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL7601076 | 0.80 | PARP1 (0.50) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL7598089 | 0.80 | PARP1 (0.50) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL2854316 | 0.79 | PARP1 (0.36) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL17243112 | 0.78 | NPSR1 (0.42) | BCL2GSK3BNPSR1PPOXWEE1 | |
| SCHEMBL19143852 | 0.78 | GSK3B (0.47) | GSK3BNPSR1PPOXWEE1CHEK1 | |
| SCHEMBL12744308 | 0.76 | NPSR1 (0.44) | BCL2GSK3BNPSR1PPOXWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10818849-B2 | Electron acceptors based on alpha-position substituted PDI for OPV solar cells | THE UNIVERSITY OF CHICAGO (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190044074-A1 | ELECTRON ACCEPTORS BASED ON ALPHA-POSITION SUBSTITUTED PDI FOR OPV SOLAR CELLS | THE UNIVERSITY OF CHICAGO (US) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190044074-A1 | ELECTRON ACCEPTORS BASED ON ALPHA-POSITION SUBSTITUTED PDI FOR OPV SOLAR CELLS | PPOX, PPIE, PIN1 | BCL2 1587/4885GSK3B 1254/4885NPSR1 4448/4885 |
| US-10818849-B2 | Electron acceptors based on alpha-position substituted PDI for OPV solar cells | PPOX, PPIE, PIN1 | BCL2 1587/4885GSK3B 1254/4885NPSR1 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.