Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20699933 | 0.85 | DHPS (0.47) | DHPSALDH1A1CA12CA9MAPK1 | |
| SCHEMBL20700305 | 0.77 | ADRA1A (0.44) | DHPSALDH1A1ADRA2AADRA1A | |
| SCHEMBL20700430 | 0.76 | ADRA2A (0.50) | DHPSADRA2AADRA1A | |
| SCHEMBL29981056 | 0.76 | ADRA2A (0.50) | DHPSADRA2AADRA1A | |
| SCHEMBL20700068 | 0.76 | ADRA2A (0.50) | DHPSADRA2AADRA1A | |
| SCHEMBL20700071 | 0.76 | ADRA2A (0.50) | DHPSADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL20700113 | 0.75 | ADRA2A (0.49) | DHPSADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL20700112 | 0.75 | ADRA2A (0.49) | DHPSADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL20700831 | 0.75 | ADRA2A (0.49) | DHPSADRA2AADRA1A | |
| SCHEMBL20718041 | 0.73 | ADRA2A (0.53) | DHPSADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028165-A1 | ISOCHROMAN COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2019-02-07 | — | — | WO | disclosed |