Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.76 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diosmetin SCHEMBL19127636 | 0.89 | CYP1B1 (0.78) | MAOAAKR1B1MAPK8LCKMAPT | |
| Chrysin SCHEMBL3858957 | 0.88 | ABCB1 (0.84) | MAOAAKR1B1LCKMAPTCYP3A4 | |
| Acacetin SCHEMBL2146352 | 0.88 | MAPT (0.79) | MAOAAKR1B1MAPTCYP3A4ALDH1A1 | |
| Tricin SCHEMBL44475 | 0.87 | MAOA (1.00) | MAOAAKR1B1MAPK8LCKMAPT | |
| Tricin SCHEMBL29712335 | 0.87 | MAOA (1.00) | MAOAAKR1B1MAPK8LCKMAPT | |
| Tricin SCHEMBL10809395 | 0.86 | MAOA (0.97) | MAOAAKR1B1MAPK8LCKMAPT | |
| Apigenin SCHEMBL3430874 | 0.85 | CYP3A4 (0.78) | MAOAAKR1B1LCKMAPTCYP3A4 | |
| SCHEMBL12378833 | 0.83 | MAOA (0.92) | MAOAAKR1B1MAPK8MAPTCYP3A4 | |
| SCHEMBL29576775 | 0.83 | MAOA (0.92) | MAOAAKR1B1MAPK8MAPTCYP3A4 | |
| Chrysin SCHEMBL28168227 | 0.83 | MAPT (0.89) | MAOAAKR1B1MAPK8LCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114869996-A | Application of amaranthus viridis polypeptide in preparation of medicine for improving ulcerative colitis | 中国药科大学 | 2022-08-09 | — | — | CN | disclosed |
| US-20210095265-A1 | IN VITRO METHODS FOR PROCESSING LIGNIN AND OTHER AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-04-01 | — | — | US | disclosed |
| US-10829745-B2 | In vitro methods for processing lignin and other aromatic compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190048329-A1 | ENZYMES AND METHODS FOR PROCESSING LIGNIN AND OTHER AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-02-14 | — | — | US | disclosed |