Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240887 | 0.83 | MEN1 (0.49) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20733619 | 0.80 | HPGD (0.42) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL11841036 | 0.75 | GSK3B (0.38) | HPGDALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1945678 | 0.70 | MEN1 (0.45) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL12564971 | 0.70 | HPGD (0.87) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL22468504 | 0.69 | CYP1A2 (0.59) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20521778 | 0.69 | SMYD3 (0.46) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL623602 | 0.69 | TSHR (0.45) | ALDH1A1MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL18099179 | 0.68 | KDM4E (0.49) | MEN1KMT2A | |
| SCHEMBL13885084 | 0.68 | P2RX7 (0.47) | HPGDALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997665-B | Pesticidally active thiophene derivatives | 先正达参股股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-11490620-B2 | Pesticidally active thiophene derivatives | SYNGENTA PARTICIPATIONS AG (SE) | 2022-11-08 | — | — | US | disclosed |
| EP-3665170-B1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| EP-3665170-B1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (SE) | 2020-08-06 | — | — | US | disclosed |
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (SE) | 2020-08-06 | — | — | US | disclosed |
| EP-3665170-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | Syngenta Participations AG (CH) | 2020-06-17 | — | — | EP | disclosed |
| CN-110997665-A | Pesticidally active thiophene derivatives | 先正达参股股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2019030357-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019030357-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | HPGD 3314/4885ALDH1A1 522/4885RAB9A 217/4885 |
| US-11490620-B2 | Pesticidally active thiophene derivatives | ACHE, DDT, GSTP1 | HPGD 3314/4885ALDH1A1 522/4885RAB9A 217/4885 |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | HPGD 3073/4885ALDH1A1 444/4885RAB9A 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.