Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733660 | 0.80 | HPGD (0.38) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20723613 | 0.80 | HPGD (0.47) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20733620 | 0.79 | HPGD (0.40) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL23240887 | 0.77 | MEN1 (0.49) | HPGDALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20885363 | 0.75 | S100A4 (0.37) | HPGDALDH1A1RAB9AS100A4NPC1 | |
| SCHEMBL20876167 | 0.75 | S100A4 (0.39) | HPGDRAB9AS100A4NPC1KCNH2 | |
| SCHEMBL20733697 | 0.74 | CTSL (0.36) | — | |
| SCHEMBL20723571 | 0.74 | XDH (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20876195 | 0.72 | KDM4E (0.43) | HPGDALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL20723582 | 0.66 | KDM4E (0.48) | ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| EP-3665170-B1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (SE) | 2020-08-06 | — | — | US | disclosed |
| WO-2019068820-A1 | PESTICIDALLY ACTIVE PYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
| WO-2019030357-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | HPGD 3314/4885ALDH1A1 522/4885RAB9A 217/4885 |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | HPGD 3073/4885ALDH1A1 444/4885RAB9A 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.