Penoxsulam

Penoxsulam

SCHEMBL20723787

COc1cnc(OC)n2nc(NS(=O)(=O)c3c(OCC(F)F)cccc3C(F)(F)F)nc12.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.32
MAPT P10636 4/20 0.31
KMT2A Q03164 4/20 0.31
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 3/20 0.31
MEN1 O00255 3/20 0.31
GAA P10253 2/20 0.31
ADORA2A P29274 1/20 0.31
CCR4 P51679 1/20 0.31
MAPK10 P53779 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
POLB P06746 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penoxsulam SCHEMBL20723908 0.90 SLC40A1 (0.32)
Penoxsulam SCHEMBL116968 0.87 PSEN1 (0.35) ALDH1A1CCR4MAPK10EDNRA
Penoxsulam SCHEMBL20723833 0.86 CCR4 (0.32) CCR4
Penoxsulam SCHEMBL22587372 0.86 PSEN1 (0.34) ALDH1A1CCR4MAPK10EDNRA
Penoxsulam SCHEMBL20723756 0.85 PTK2 (0.33) KDM4EALDH1A1CCR4MAPK10EDNRA
Penoxsulam SCHEMBL20723816 0.83 PTK2 (0.30)
Penoxsulam SCHEMBL10325449 0.82 PTK2 (0.33) CCR4MAPK10
Penoxsulam SCHEMBL20723903 0.81 CCR2 (0.33) MAPK10
Penoxsulam SCHEMBL20723714 0.81 SLC40A1 (0.33) MAPK10
SCHEMBL17864141 0.81 EDNRA (0.34) ALDH1A1CCR4MAPK10EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3664609-A1 SYNERGISTIC HERBICIDAL COMBINATIONS UPL Ltd (IN) 2020-06-17 EP disclosed
WO-2019030614-A1 SYNERGISTIC HERBICIDAL COMBINATIONS UPL LTD (IN) 2019-02-14 WO disclosed