SCHEMBL2072452

SCHEMBL2072452

CN(C)c1ccc(/C=C(\C#N)C(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
KMT2A Q03164 10/20 1.00
MAPT P10636 7/20 1.00
MEN1 O00255 5/20 1.00
KDM4E B2RXH2 2/20 0.68
PKM P14618 2/20 0.68
ATM Q13315 1/20 0.68
RAB9A P51151 2/20 0.65
MAPK1 P28482 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
LMNA P02545 2/20 0.62
GAA P10253 1/20 0.62
EGFR P00533 1/20 0.60
ERBB2 P04626 1/20 0.60
IDE P14735 2/20 0.57
POLB P06746 2/20 0.56
USP2 O75604 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7896356 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL2072454 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL9642804 0.87 ALDH1A1 (0.78) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL9642815 0.87 ALDH1A1 (0.78) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL8965782 0.87 ALDH1A1 (0.78) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL8965459 0.86 KMT2A (0.76) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL2957854 0.85 ALDH1A1 (0.79) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL19888568 0.85 ALDH1A1 (0.79) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL20959563 0.85 ALDH1A1 (0.79) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL6229935 0.84 MAPT (0.72) ALDH1A1KMT2AMAPTMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912075-B1 CATIONICALLY CROSS-LINKABLE/POLYMERISABLE COMPOSITION COMPRISING AN IODONIUM BORATE AND RELEASING AN ACCEPTABLE ODOUR BLUESTAR SILICONES FRANCE (FR) 2016-12-14 EP disclosed
EP-2904021-B1 CATIONICALLY CROSS-LINKABLE/POLYMERIZABLE ORGANIC RESIN COMPOSITION COMPRISING AN IODONIUM BORATE AND HAVING AN ACCEPTABLE SMELL BLUESTAR SILICONES FRANCE (FR) 2016-12-07 EP disclosed
EP-2912075-A1 CATIONICALLY CROSS-LINKABLE/POLYMERISABLE COMPOSITION COMPRISING AN IODONIUM BORATE AND RELEASING AN ACCEPTABLE ODOUR Bluestar Silicones France SAS (FR) 2015-09-02 EP disclosed
EP-2904021-A1 CATIONICALLY CROSS-LINKABLE/POLYMERIZABLE ORGANIC RESIN COMPOSITION COMPRISING AN IODONIUM BORATE AND HAVING AN ACCEPTABLE SMELL Bluestar Silicones France SAS (FR) 2015-08-12 EP disclosed
WO-2014053714-A1 CATIONICALLY CROSS-LINKABLE/POLYMERISABLE COMPOSITION COMPRISING AN IODONIUM BORATE AND RELEASING AN ACCEPTABLE ODOUR BLUESTAR SILICONES FRANCE SAS (FR) 2014-04-10 WO disclosed
WO-2014053231-A1 CATIONICALLY CROSS-LINKABLE/POLYMERIZABLE ORGANIC RESIN COMPOSITION COMPRISING AN IODONIUM BORATE AND HAVING AN ACCEPTABLE SMELL BLUESTAR SILICONES FRANCE SAS (FR) 2014-04-10 WO disclosed
US-7901867-B2 Sulphonium salt initiators BASF SE (DE) 2011-03-08 US disclosed
EP-1902019-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-07-07 EP disclosed
US-20090208872-A1 Sulphonium Salt Initiators BASF SE (DE) 2009-08-20 US disclosed
EP-1902019-A1 SULPHONIUM SALT INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2008-03-26 EP disclosed
WO-2005070989-A2 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-08-04 WO disclosed
US-20050165141-A1 Thermally stable cationic photocurable compositions CIBA SPECIALTY CHEMICALS CORP. 2005-07-28 US disclosed
EP-0672953-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 2003-01-15 EP disclosed
US-20010036591-A1 Iodonium salts as latent acid donors IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6306555-B1 RADIATION-SENSITIVE COMPOSITION COMPRISING CATIONICALLY OR ACID-CATALYTICALLY POLYMERISABLE OR CROSSLINKABLE COMPOUND OR COMPOUND THAT INCREASES ITS SOLUBILITY IN DEVELOPER UNDER ACTION OF ACID, AND AT LEAST ONE DIARYLIODONIUM SALT CIBA SPECIALTY CHEMICALS CORP. 2001-10-23 US disclosed
US-6045953-A COMPRISES A SUBSTRATE, A PHOTOSENSITIVE LAYER FORMED ON THE SUBSTRATE BY COATING A PHOTOSENSITIVE SOLUTION CONTAINING AN ALICYCLIC, SOLVENT SOLUBLE, CATIONIC POLYMERIZABLE EPOXY RESIN AND AN ACRYLATE POLYMER TOPPAN PRINTING CO., LTD. (JP) 2000-04-04 US disclosed
EP-0697631-B1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium TOPPAN PRINTING CO LTD (JP) 1998-06-10 EP disclosed
US-5698345-A CATIONIC POLYMERIZATION OF THERMOSETTING EPOXY OLIGOMER TOPPAN PRINTING CO., LTD. (JP) 1997-12-16 US disclosed
EP-0697631-A1 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1996-02-21 EP disclosed
EP-0672953-A2 Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium Toppan Printing Co., Ltd. (JP) 1995-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208872-A1 Sulphonium Salt Initiators OR10J3, OXSR1, ARSA ALDH1A1 943/4885KMT2A 1924/4885MAPT 3413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.