Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823280 | 1.00 | KDM4E (0.33) | KDM4EMEN1AKR1B10ALOX5KMT2A | |
| SCHEMBL12241230 | 1.00 | KDM4E (0.33) | KDM4EMEN1AKR1B10ALOX5KMT2A | |
| SCHEMBL13350546 | 0.90 | KDM4E (0.34) | KDM4EMEN1AKR1B10ALOX5KMT2A | |
| SCHEMBL16906165 | 0.88 | KDM4E (0.32) | KDM4EMEN1AKR1B10ALOX5KMT2A | |
| SCHEMBL14069391 | 0.86 | SLC25A5 (0.30) | KDM4EMEN1AKR1B10ALOX5KMT2A | |
| SCHEMBL20725766 | 0.85 | PTPN1 (0.37) | KDM4E | |
| SCHEMBL20725713 | 0.83 | — | — | |
| SCHEMBL823176 | 0.83 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL13922245 | 0.81 | — | — | |
| SCHEMBL22422584 | 0.81 | SLC25A5 (0.31) | KDM4EMEN1AKR1B10ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870133-B1 | TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING | KINDEX PHARMACEUTICALS INC (US) | 2019-02-13 | — | — | EP | disclosed |