Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | FASN | P49327 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12241230 | 0.85 | KDM4E (0.33) | KDM4E | |
| SCHEMBL13823280 | 0.85 | KDM4E (0.33) | KDM4E | |
| SCHEMBL20725736 | 0.85 | KDM4E (0.33) | KDM4E | |
| SCHEMBL823176 | 0.80 | ALOX5 (0.31) | — | |
| SCHEMBL31362119 | 0.79 | FASN (0.34) | PTPN1FASNSMN1; SMN2MAPTACP1 | |
| SCHEMBL13823277 | 0.79 | KDM4E (0.31) | MAPTKDM4E | |
| SCHEMBL20725713 | 0.75 | — | — | |
| SCHEMBL16906165 | 0.73 | KDM4E (0.32) | KDM4E | |
| SCHEMBL14069391 | 0.72 | SLC25A5 (0.30) | KDM4E | |
| SCHEMBL20714419 | 0.71 | KDM4E (0.30) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870133-B1 | TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING | KINDEX PHARMACEUTICALS INC (US) | 2019-02-13 | — | — | EP | disclosed |