Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726414 | 0.79 | MTNR1A (0.45) | — | |
| SCHEMBL20726395 | 0.75 | PRKAB2 (0.57) | HTR3AHRH3KDM4EHRH1 | |
| SCHEMBL20726492 | 0.74 | PRKAB2 (0.56) | HTR3AHRH3KDM4EHRH1 | |
| SCHEMBL20726379 | 0.72 | PRKAB2 (0.44) | MAOB | |
| SCHEMBL20726478 | 0.71 | AURKA (0.39) | — | |
| SCHEMBL20726351 | 0.70 | BRD4 (0.41) | — | |
| SCHEMBL20726357 | 0.69 | BRD4 (0.40) | ACHE | |
| SCHEMBL12050645 | 0.69 | HRH3 (1.00) | HRH3KCNH2HRH1 | |
| SCHEMBL4094339 | 0.69 | HRH3 (1.00) | HRH3KCNH2HRH1 | |
| SCHEMBL7061367 | 0.68 | KDM4E (0.48) | HRH3BCHEACHEKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083611-B1 | OXINDOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE IN THE TREATMENT OF AMPK-RELATED DISEASES | SANOFI SA (FR) | 2019-02-13 | — | — | EP | disclosed |