Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726369 | 0.79 | KDR (0.40) | MAOAKDR | |
| SCHEMBL20726489 | 0.77 | PRKAB2 (0.49) | — | |
| SCHEMBL20726485 | 0.76 | ERCC1 (0.40) | MAOAKDR | |
| SCHEMBL20726499 | 0.76 | BRD4 (0.37) | KDM1AMAOAKDR | |
| SCHEMBL20726385 | 0.73 | PRKAB2 (0.38) | — | |
| SCHEMBL20726365 | 0.73 | PBK (0.41) | MAOAKDR | |
| SCHEMBL20726452 | 0.73 | EGFR (0.40) | KDR | |
| SCHEMBL20726481 | 0.72 | ERBB2 (0.40) | MAOAKDR | |
| SCHEMBL20726480 | 0.72 | PRKAB2 (0.39) | KDM1AKDR | |
| SCHEMBL20726482 | 0.72 | ERBB2 (0.42) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083611-B1 | OXINDOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE IN THE TREATMENT OF AMPK-RELATED DISEASES | SANOFI SA (FR) | 2019-02-13 | — | — | EP | disclosed |