Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726481 | 0.83 | ERBB2 (0.40) | CHEK1KDR | |
| SCHEMBL20726482 | 0.82 | ERBB2 (0.42) | CHEK1KDR | |
| SCHEMBL20726429 | 0.81 | CHEK1 (0.44) | CHEK1 | |
| SCHEMBL20726510 | 0.78 | AR (0.41) | SYK | |
| SCHEMBL20726485 | 0.75 | ERCC1 (0.40) | CHEK1KDR | |
| SCHEMBL20726369 | 0.75 | KDR (0.40) | CHEK1KDR | |
| SCHEMBL20726432 | 0.73 | CDK1 (0.36) | SYK | |
| SCHEMBL20726500 | 0.73 | CDK1 (0.36) | SYK | |
| SCHEMBL20726434 | 0.71 | ERBB2 (0.39) | CHEK1 | |
| SCHEMBL20726452 | 0.70 | EGFR (0.40) | CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083611-B1 | OXINDOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE IN THE TREATMENT OF AMPK-RELATED DISEASES | SANOFI SA (FR) | 2019-02-13 | — | — | EP | disclosed |