Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945563 | 0.80 | GABRA1 (0.47) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL15945561 | 0.76 | GABRA1 (0.47) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL14829717 | 0.76 | GABRA1 (0.44) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL14829230 | 0.72 | CCR1 (0.47) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL19736052 | 0.68 | ALDH1A1 (0.39) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL10365943 | 0.67 | ALDH1A1 (0.47) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL22216205 | 0.67 | SMN1; SMN2 (0.43) | MAPK1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16827295 | 0.66 | ADRA1A (0.57) | CYP1A2 | |
| SCHEMBL4696401 | 0.66 | ALDH1A1 (0.37) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL28425324 | 0.66 | SMN1; SMN2 (0.43) | MAPK1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864337-B1 | ANTIMICROBIAL COMPOUNDS | UNIV OXFORD INNOVATION LTD (GB) | 2019-02-13 | — | — | EP | disclosed |