Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608124 | 0.78 | GAA (1.00) | GAARAB9ANPC1GFERPOLB | |
| SCHEMBL28871831 | 0.73 | GAA (0.76) | GAARAB9ANPC1L3MBTL1GFER | |
| SCHEMBL16672404 | 0.72 | GAA (0.60) | GAARAB9ANPC1L3MBTL1GFER | |
| SCHEMBL20984862 | 0.70 | GAA (0.67) | GAARAB9ANPC1GFERPOLB | |
| SCHEMBL31006493 | 0.70 | GAA (0.69) | GAARAB9ANPC1L3MBTL1POLB | |
| SCHEMBL28871770 | 0.70 | GAA (0.69) | GAARAB9ANPC1L3MBTL1POLB | |
| SCHEMBL3370719 | 0.69 | POLB (0.59) | RAB9ANPC1L3MBTL1EPHX2POLB | |
| SCHEMBL6918970 | 0.69 | L3MBTL1 (0.53) | GAARAB9AL3MBTL1EPHX2POLB | |
| SCHEMBL3229167 | 0.69 | GAA (0.68) | GAARAB9ANPC1L3MBTL1GFER | |
| SCHEMBL11704238 | 0.68 | ALDH1A1 (0.56) | RAB9ANPC1L3MBTL1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |