Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN2B | O60939 | 1/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16672364 | 0.89 | NPC1 (0.42) | GAAPOLBSMN1; SMN2SCN2BSCN1B | |
| SCHEMBL20726634 | 0.80 | GAA (0.56) | GAAPOLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL16672323 | 0.74 | L3MBTL1 (0.46) | GAARIPK1SMN1; SMN2SCN2BSCN1B | |
| SCHEMBL16474405 | 0.74 | ALDH1A1 (0.45) | GAAPOLBSMN1; SMN2SCN2BSCN1B | |
| SCHEMBL16672343 | 0.74 | MEN1 (0.42) | GAAPOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL1827711 | 0.73 | SMN1; SMN2 (0.70) | GAAPOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL25078533 | 0.73 | ALDH1A1 (0.48) | GAASMN1; SMN2SCN2BSCN1BSCN5A | |
| SCHEMBL30949243 | 0.73 | ALDH1A1 (0.48) | GAASMN1; SMN2SCN2BSCN1BSCN5A | |
| SCHEMBL30159505 | 0.72 | PTGS1 (0.44) | GAASMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16672403 | 0.72 | PTGS1 (0.44) | GAASMN1; SMN2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |