SCHEMBL20726693

SCHEMBL20726693

N#Cc1ccc(-c2nc(-c3cccc(-c4ccc5ccc6cccnc6c5n4)c3)nc(-c3cccc(-c4ccc5ccc6cccnc6c5n4)c3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 1/20 0.43
FABP1 P07148 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
CYP11B2 P19099 4/20 0.41
CYP11B1 P15538 3/20 0.41
CYP17A1 P05093 1/20 0.41
GLO1 Q04760 1/20 0.41
SLC40A1 Q9NP59 1/20 0.40
ABCG2 Q9UNQ0 4/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
HSP90AA1 P07900 1/20 0.39
MMP2 P08253 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20726871 0.99 CYP11B2 (0.43) CLK4FABP1PDE4APDE4CPDE4D
SCHEMBL20726692 0.91 KDM4E (0.44) FABP1PDE4APDE4CPDE4DCYP11B2
SCHEMBL20732504 0.90 CYP11B2 (0.44) FABP1PDE4APDE4CPDE4DCYP11B2
SCHEMBL20732550 0.89 KDM4E (0.44) FABP1PDE4APDE4CPDE4DCYP11B2
SCHEMBL20726824 0.88 PDE4A (0.44) FABP1PDE4APDE4CPDE4DCYP11B2
SCHEMBL20726738 0.87 CYP11B2 (0.44) FABP1PDE4APDE4CPDE4DCYP11B2
SCHEMBL20732549 0.87 CCR1 (0.52) KDM4EGMNNLMNATP53HSP90AA1
SCHEMBL21709041 0.86 MAPT (0.44) KDM4EGMNNLMNATP53HSP90AA1
SCHEMBL20726691 0.86 MAPT (0.44) KDM4EGMNNLMNATP53HSP90AA1
SCHEMBL16026752 0.86 MAPT (0.44) KDM4EGMNNLMNATP53HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441391-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2020-09-02 EP disclosed
US-20190051841-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed
EP-3441391-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051841-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC2, CYP1A1, CRY1 CLK4 1888/4885FABP1 4643/4885PDE4A 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.