Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20726728 | 0.94 | CYP17A1 (0.46) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726759 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726758 | 0.90 | CYP17A1 (0.45) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726820 | 0.88 | MAPT (0.46) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL30446461 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL22689545 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726818 | 0.87 | MAPT (0.44) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726744 | 0.86 | MAPT (0.50) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL20726812 | 0.86 | LMNA (0.53) | SMN1; SMN2KDM4ECCR1CCR5CCR8 | |
| SCHEMBL25793995 | 0.86 | RARB (0.44) | SMN1; SMN2KDM4ECCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190051841-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-02-14 | — | — | US | disclosed |
| EP-3441391-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2019-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190051841-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | AOC2, CYP1A1, CRY1 | SMN1; SMN2 4204/4885KDM4E 4165/4885CCR1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.