Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035507 | 0.87 | KDM4E (0.37) | ERN1CGASKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29556596 | 0.87 | KDM4E (0.37) | ERN1CGASKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20727054 | 0.82 | CGAS (0.38) | ERN1CGASKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20727098 | 0.80 | RAB9A (0.45) | KDM4EALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL16035711 | 0.79 | NEK2 (0.40) | ABCB1ABCC1 | |
| SCHEMBL29556583 | 0.79 | NEK2 (0.40) | ABCB1ABCC1 | |
| SCHEMBL20727082 | 0.77 | ERCC1 (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL719542 | 0.74 | ERN1 (0.39) | ERN1KDM4EALDH1A1SMN1; SMN2PKM | |
| SCHEMBL16075374 | 0.74 | SLC6A3 (0.43) | KDM4EALDH1A1SMN1; SMN2RAB9APKM | |
| SCHEMBL16075461 | 0.73 | KDM4E (0.40) | CGASKDM4EALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |