Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.38 |
| ▸ | DHPS | P49366 | 8/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035711 | 1.00 | NEK2 (0.40) | NEK2ABCB1DHPSABCC1TPMT | |
| SCHEMBL29556596 | 0.89 | KDM4E (0.37) | NEK2ABCB1DHPSABCC1 | |
| SCHEMBL16035507 | 0.89 | KDM4E (0.37) | NEK2ABCB1DHPSABCC1 | |
| SCHEMBL20727040 | 0.87 | KMO (0.43) | NEK2ABCB1DHPSABCC1PDE4B | |
| SCHEMBL1397142 | 0.86 | KMO (0.44) | NEK2DHPS | |
| SCHEMBL16036648 | 0.86 | NEK2 (0.40) | NEK2ABCB1DHPSABCC1TPMT | |
| SCHEMBL29556640 | 0.86 | NEK2 (0.40) | NEK2ABCB1DHPSABCC1TPMT | |
| SCHEMBL16075425 | 0.84 | KIF11 (0.45) | NEK2 | |
| SCHEMBL16075438 | 0.82 | DHPS (0.52) | NEK2DHPSTPMT | |
| SCHEMBL16075453 | 0.82 | TPMT (0.36) | NEK2ABCB1DHPSABCC1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689924-B | 4-amino-6- (4-substituted phenyl) -pyridine-2-carboxylic acid esters and their use as herbicides | 美国陶氏益农公司 | 2022-04-12 | — | — | CN | disclosed |