Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | VRK2 | Q86Y07 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727092 | 0.84 | KMO (0.46) | KDM4ELMNAHSD17B10ERN1AKR1C2 | |
| SCHEMBL29556640 | 0.83 | NEK2 (0.40) | KIF11CYP1A2HSD17B10 | |
| SCHEMBL16036648 | 0.83 | NEK2 (0.40) | KIF11CYP1A2HSD17B10 | |
| SCHEMBL20727056 | 0.75 | CYP1A1 (0.49) | CYP1A2KDM4EHSD17B10CYP1A1CYP1B1 | |
| SCHEMBL29556105 | 0.74 | KIF11 (0.40) | KIF11CYP1A2KDM4EHSD17B10 | |
| SCHEMBL16036360 | 0.74 | KIF11 (0.40) | KIF11CYP1A2KDM4EHSD17B10 | |
| SCHEMBL16036088 | 0.70 | KIF11 (0.40) | KIF11ESR1ESR2EPRS1 | |
| SCHEMBL29556686 | 0.70 | KIF11 (0.40) | KIF11ESR1ESR2EPRS1 | |
| SCHEMBL16036615 | 0.70 | TDP1 (0.44) | KIF11 | |
| SCHEMBL29556604 | 0.70 | TDP1 (0.44) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |