Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727094 | 0.84 | KIF11 (0.41) | AKR1C2ERN1AKR1C1KDM4EHSD17B10 | |
| SCHEMBL20727040 | 0.84 | KMO (0.43) | KMORARARARBRARGAKR1C3 | |
| SCHEMBL16075374 | 0.75 | SLC6A3 (0.43) | KMOHDAC1HDAC6KDM4EHSD17B10 | |
| SCHEMBL20727056 | 0.75 | CYP1A1 (0.49) | KDM4EHSD17B10KMT2AALDH1A1 | |
| SCHEMBL20727068 | 0.73 | ERN1 (0.39) | ERN1KDM4EHSD17B10LMNAXDH | |
| SCHEMBL20727085 | 0.70 | KMO (0.51) | KMOHDAC1HDAC6AKR1C3AKR1C2 | |
| SCHEMBL20727066 | 0.70 | KMO (0.45) | KMOAKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL1397142 | 0.70 | KMO (0.44) | KMOKDM4EHSD17B10PDE4DALDH1A1 | |
| SCHEMBL16036648 | 0.70 | NEK2 (0.40) | HSD17B10PDE4B | |
| SCHEMBL16035711 | 0.70 | NEK2 (0.40) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |