Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 13/20 | 0.34 |
| ▸ | EED | O75530 | 9/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 9/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 9/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 9/20 | 0.34 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727202 | 0.82 | PDE4B (0.34) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20727204 | 0.72 | EZH2 (0.35) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20727168 | 0.71 | PDE4B (0.43) | PDE4BKMT2AIDO1HDAC1HDAC6 | |
| SCHEMBL28466809 | 0.71 | EZH2 (0.41) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20727206 | 0.69 | EZH2 (0.33) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20727150 | 0.69 | PDE4B (0.33) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL25933018 | 0.64 | GBA1 (0.51) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL18365032 | 0.64 | EZH2 (0.55) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL29180269 | 0.64 | EZH2 (0.39) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL27074905 | 0.63 | JAK2 (0.33) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441388-A1 | 4,5,6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2019-02-13 | — | — | EP | disclosed |