Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 11/20 | 0.34 |
| ▸ | EED | O75530 | 10/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 10/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 10/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 10/20 | 0.34 |
| ▸ | EZH1 | Q92800 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727144 | 0.82 | EZH2 (0.34) | PDE4BEZH2EEDRBBP4SUZ12 | |
| SCHEMBL20727222 | 0.80 | GRIN2B (0.35) | — | |
| SCHEMBL20727230 | 0.80 | S1PR1 (0.34) | EZH2EZH1 | |
| SCHEMBL20727204 | 0.76 | EZH2 (0.35) | PDE4BEZH2EEDRBBP4SUZ12 | |
| SCHEMBL20727150 | 0.73 | PDE4B (0.33) | PDE4BEZH2EEDRBBP4SUZ12 | |
| SCHEMBL20727201 | 0.71 | PDE4B (0.46) | PDE4BIDO1TDO2 | |
| SCHEMBL28466809 | 0.71 | EZH2 (0.41) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20727206 | 0.69 | EZH2 (0.33) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL27074905 | 0.68 | JAK2 (0.33) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20160784 | 0.65 | EZH2 (0.35) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262812-A1 | 4, 5, 6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN MEDICINES | YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-08-20 | — | — | US | disclosed |
| EP-3441388-A1 | 4,5,6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2019-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262812-A1 | 4, 5, 6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN MEDICINES | CYP3A4, CYP4B1, CYP3A7 | PDE4B 185/4885EZH2 1830/4885EED 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.