Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20729674 | 1.00 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL26332822 | 0.84 | NR1H2 (0.35) | NR1H2KLK7PREPHSD17B10SMN1; SMN2 | |
| SCHEMBL20729517 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL20729593 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL20729652 | 0.82 | NR1H2 (0.34) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL22604250 | 0.77 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL20729577 | 0.77 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL29548240 | 0.77 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BKLK7 | |
| SCHEMBL24047038 | 0.75 | EPHX1 (0.34) | NR1H2NR1H3PDE4BKLK7CCR2 | |
| SCHEMBL20729563 | 0.75 | EPHX1 (0.34) | NR1H2NR1H3PDE4BKLK7CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-20220073554-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-03-10 | — | — | US | disclosed |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-09-21 | — | — | US | disclosed |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-10-29 | — | — | US | disclosed |
| WO-2019032936-A1 | LINCONSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT ADN FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | NR1H2 3390/4885NR1H3 3351/4885PTPN1 2523/4885 |
| US-11124534-B2 | Lincosamide antibiotics and uses thereof | LNPEP, LCLAT1, NPEPPS | NR1H2 3390/4885NR1H3 3351/4885PTPN1 2523/4885 |
| US-20220073554-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | NR1H2 3233/4885NR1H3 3331/4885PTPN1 2516/4885 |
| US-20200339620-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | LNPEP, LCLAT1, NPEPPS | NR1H2 3390/4885NR1H3 3351/4885PTPN1 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.