SCHEMBL2072999

SCHEMBL2072999

O=C1c2ccccc2-c2cccc(F)c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MAOA P21397 4/20 0.52
MAPK1 P28482 3/20 0.52
LMNA P02545 2/20 0.52
PTPRC P08575 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
KDM4E B2RXH2 2/20 0.52
RECQL P46063 2/20 0.52
NPC1 O15118 2/20 0.52
S100A4 P26447 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CES2 O00748 1/20 0.52
APAF1 O14727 1/20 0.52
TERT O14746 1/20 0.52
PLIN1 O60240 1/20 0.52
TDP2 O95551 1/20 0.52
S1PR4 O95977 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13487411 0.95 PTPRC (0.59) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL760904 0.91 ADORA2A (0.57) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL5866470 0.88 CA1 (0.52) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL10716838 0.88 MAOA (0.52) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL3418850 0.83 MEN1 (0.55) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL9810988 0.82 PTPN1 (0.47) MAPTLMNAPTPRCPOLBALDH1A1
SCHEMBL13487410 0.82 PTPRC (0.57) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL8669578 0.82 MEN1 (0.55) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL8916299 0.81 MAPT (0.54) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL6655232 0.80 PDK2 (0.44) MAPTMEN1KMT2AMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110218501-A A kind of preparation method of the polyether-ether-ketone enamel new material with superior heat-stability 宁波高新区诠宝绶新材料科技有限公司 2019-09-10 CN claimed
CN-109233540-A A kind of preparation method of the polyether-ether-ketone enamel new material with superior heat-stability 宁波高新区诠宝绶新材料科技有限公司 2019-01-18 CN claimed
CN-117024426-A Carbazole derivative and application thereof 浙江八亿时空先进材料有限公司 2023-11-10 CN disclosed
CN-106468862-B Electrophotography photodetector, handle box and image forming apparatus 富士施乐株式会社 2019-11-08 CN disclosed
CN-110218501-A A kind of preparation method of the polyether-ether-ketone enamel new material with superior heat-stability 宁波高新区诠宝绶新材料科技有限公司 2019-09-10 CN disclosed
CN-110023073-A Multi-layer adhesive product 3M创新有限公司 2019-07-16 CN disclosed
CN-109689826-A Rapid curing optical adhesive 3M创新有限公司 2019-04-26 CN disclosed
CN-105384611-B A kind of electron donor of Ziegler-Natta catalyst and preparation method thereof 亚培烯科技(杭州)有限公司 2019-04-19 CN disclosed
CN-105330508-B One kind 3 is monosubstituted or 3,6 2 replace fluorene derivative and its preparation method and application 亚培烯科技(杭州)有限公司 2019-04-19 CN disclosed
CN-106029046-B Dental composition and application thereof 3M创新有限公司 2019-04-05 CN disclosed
CN-109233540-A A kind of preparation method of the polyether-ether-ketone enamel new material with superior heat-stability 宁波高新区诠宝绶新材料科技有限公司 2019-01-18 CN disclosed
CN-1326457-A 4-aminopyrrolopyrimidines as kinase inhibitors BASF AG (DE) 2001-12-12 CN disclosed
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed
EP-0092385-B1 HYDANTOIN DERIVATIVES FOR USE IN INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOREN COMPOUNDS ALCON LABORATORIES, INC. (US) 1991-06-12 EP disclosed
EP-0290133-A2 Ternary photoinitiator system for addition polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-11-09 EP disclosed
US-4540700-A Treatment of diabetic complications with certain spiro-imidazolidine-diones ALCON LABORATORIES, INC. (US) 1985-09-10 US disclosed
US-4438272-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1984-03-20 US disclosed
US-4436745-A TETRACYCLIC SPIROHYDANTOINS ALCON LABORATORIES, INC. (US) 1984-03-13 US disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed