Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978164 | 1.00 | PTPN1 (0.44) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16299195 | 1.00 | PTPN1 (0.44) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL28331635 | 0.92 | PTPN1 (0.46) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL18654300 | 0.92 | PTPN1 (0.46) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16632144 | 0.92 | PTPN1 (0.46) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16632142 | 0.92 | PTPN1 (0.46) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16299814 | 0.92 | USP2 (0.42) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL19772808 | 0.92 | PTPN1 (0.39) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL16632198 | 0.91 | PTPN1 (0.42) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL31092625 | 0.90 | PTPN1 (0.46) | PTPN1USP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110174-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-10806791-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200297853-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | BANK OF AMERICA, N.A. | 2020-09-24 | — | — | US | disclosed |
| US-20190184018-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | BANK OF AMERICA, N.A. | 2019-06-20 | — | — | US | disclosed |
| US-20190099493-A1 | Targeting Lipids | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-04-04 | — | — | US | disclosed |
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS INC (US) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | PTPN1 880/4885USP2 4435/4885MEN1 216/4885 |
| US-20190184018-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | SLC2A2, SLC2A8, SLC2A1 | PTPN1 2198/4885USP2 3449/4885MEN1 2703/4885 |
| US-20200297853-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | SLC2A2, SLC2A8, SLC2A1 | PTPN1 2198/4885USP2 3449/4885MEN1 2703/4885 |
| US-10806791-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | SLC2A2, SLC2A8, SLC2A1 | PTPN1 2198/4885USP2 3449/4885MEN1 2703/4885 |
| US-11110174-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | SLC2A2, SLC2A8, SLC2A1 | PTPN1 2198/4885USP2 3449/4885MEN1 2703/4885 |
| US-20190099493-A1 | Targeting Lipids | APOB, LY96, ABHD10 | PTPN1 2396/4885USP2 1110/4885MEN1 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.