SCHEMBL20733345

SCHEMBL20733345

CCS(=O)(=O)C1=CC(=N)C(=O)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.41
S100A4 P26447 5/20 0.40
CDC25B P30305 5/20 0.40
CDC25A P30304 3/20 0.40
PTPN1 P18031 2/20 0.40
MAP2K7 O14733 2/20 0.40
PSIP1 O75475 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
PTPRC P08575 2/20 0.38
SOAT1 P35610 2/20 0.38
MAPT P10636 5/20 0.37
LMNA P02545 4/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
RAB9A P51151 4/20 0.37
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 3/20 0.37
NPC1 O15118 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
BLM P54132 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18419664 0.81 SLC2A1 (0.43) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL18713470 0.80 SLC2A1 (0.42) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL18713287 0.79 LMNA (0.39) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL25780836 0.79 PTPN1 (0.40) S100A4CDC25BCDC25APTPN1MAP2K7
SCHEMBL14428558 0.78 SLC2A1 (0.43) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL21344827 0.78 SLC2A1 (0.43) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL20344209 0.78 SLC2A1 (0.43) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL18473411 0.77 SLC2A1 (0.40) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL12419647 0.77 MAPT (0.42) SLC2A1S100A4CDC25BCDC25APTPN1
SCHEMBL25780886 0.76 NPC1 (0.36) SLC2A1S100A4CDC25BCDC25APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190049842-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION HD MICROSYSTEMS, LTD. (JP) 2019-02-14 US disclosed