SCHEMBL21344827

SCHEMBL21344827

N=C1C=C(S(=O)(=O)I)c2ccccc2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.43
S100A4 P26447 3/20 0.42
PTPN1 P18031 4/20 0.42
CDC25B P30305 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 5/20 0.39
TDP2 O95551 3/20 0.39
MAPK1 P28482 3/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
BLM P54132 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
RAB9A P51151 3/20 0.39
PTPRC P08575 3/20 0.39
APAF1 O14727 2/20 0.39
PLIN1 O60240 2/20 0.39
PLA2G1B P04054 2/20 0.39
MAOA P21397 2/20 0.39
PLIN5 Q00G26 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344209 0.81 SLC2A1 (0.43) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL18419664 0.81 SLC2A1 (0.43) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL14428558 0.81 SLC2A1 (0.43) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL18713470 0.79 SLC2A1 (0.42) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL20653100 0.78 HTR6 (0.45) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL20733345 0.78 SLC2A1 (0.41) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL12419647 0.77 MAPT (0.42) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL18473411 0.77 SLC2A1 (0.40) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL19101799 0.74 SLC2A1 (0.38) SLC2A1S100A4PTPN1CDC25BMEN1
SCHEMBL18713287 0.72 LMNA (0.39) SLC2A1S100A4PTPN1CDC25BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 US disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed
US-20190278176-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME AND ELECTRONIC DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 SLC2A1 3238/4885S100A4 1463/4885PTPN1 2274/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 SLC2A1 3184/4885S100A4 1786/4885PTPN1 2323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.