Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561334 | 1.00 | ADAMTS4 (0.41) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL15099992 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AGAASPHK1 | |
| SCHEMBL12285446 | 0.88 | PLG (0.44) | SMN1; SMN2NPC1RAB9AGAAHTT | |
| SCHEMBL24101234 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AGAASPHK1 | |
| SCHEMBL25993246 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AGAASPHK1 | |
| SCHEMBL20067564 | 0.88 | USP2 (0.45) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL14862556 | 0.88 | HTT (0.43) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL17593772 | 0.88 | HTT (0.43) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL22508222 | 0.85 | MEN1 (0.42) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL23071931 | 0.85 | USP2 (0.41) | ADAMTS4SMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173087-A1 | ANTIBODY DRUG CONJUGATES WITH CLEAVABLE LINKERS | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| WO-2019030171-A1 | NOVEL METHOD FOR SYNTHESIZING AMANITINS | HEIDELBERG PHARMA GMBH (DE) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173087-A1 | ANTIBODY DRUG CONJUGATES WITH CLEAVABLE LINKERS | C3AR1, CD38, CD47 | ADAMTS4 221/4885SMN1; SMN2 3560/4885NPC1 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.