Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KLK7 | P49862 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561334 | 0.85 | ADAMTS4 (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20733348 | 0.85 | ADAMTS4 (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20067564 | 0.84 | USP2 (0.45) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL17593772 | 0.84 | HTT (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14862556 | 0.84 | HTT (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23071931 | 0.82 | USP2 (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20149309 | 0.81 | HTT (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL22546078 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2AKLK7SMN1; SMN2NPC1 | |
| SCHEMBL19277932 | 0.81 | MEN1 (0.56) | MEN1KMT2AADAMTS4 | |
| SCHEMBL22815478 | 0.81 | MEN1 (0.56) | MEN1KMT2AADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205564-A1 | CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES | IMMUNOGEN, INC. (US) | 2020-10-08 | — | — | WO | disclosed |