SCHEMBL20067564

SCHEMBL20067564

CC(=O)N[C@H](C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 1/20 0.45
▸ MEN1 O00255 4/20 0.43
▸ KMT2A Q03164 4/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ HTT P42858 1/20 0.41
▸ ADAMTS4 O75173 2/20 0.40
▸ LMNA P02545 3/20 0.40
▸ GAA P10253 1/20 0.40
▸ POLB P06746 1/20 0.38
▸ TP53 P04637 1/20 0.37
▸ CASP1 P29466 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14862556 0.89 HTT (0.43) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL17593772 0.89 HTT (0.43) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL22561334 0.88 ADAMTS4 (0.41) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL20733348 0.88 ADAMTS4 (0.41) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL23071931 0.87 USP2 (0.41) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL19361954 0.86 USP2 (0.39) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL25921603 0.85 SMN1; SMN2 (0.47) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL17706677 0.85 MAPT (0.51) USP2MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL22508222 0.84 MEN1 (0.42) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL20149309 0.84 HTT (0.50) USP2MEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090173-A1 MODIFIED SELF-IMMOLATING MOIETIES IN ANTIBODY-DRUG CONJUGATES CODEABLE THERAPEUTICS, INCORPORATED (US) 2026-04-30 — — WO disclosed
US-20200297859-A1 NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF BYONDIS B.V. (NL) 2020-09-24 — — US disclosed
EP-3525826-B1 NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF BYONDIS BV (NL) 2020-07-22 — — EP disclosed
WO-2018069375-A1 NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF SYNTHON BIOPHARMACEUTICALS B.V. (NL) 2018-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297859-A1 NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF DLST, ADSL, LANCL1 USP2 1470/4885MEN1 3872/4885KMT2A 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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