Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21065614 | 0.91 | LMNA (0.53) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL446580 | 0.84 | ALDH1A1 (0.54) | TSHRL3MBTL1TDP1ALDH1A1LMNA | |
| SCHEMBL7695880 | 0.81 | TSHR (0.46) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL19924702 | 0.77 | TSHR (0.50) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL316833 | 0.76 | TSHR (0.53) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL17555983 | 0.76 | ALDH1A1 (0.49) | TSHRL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5099862 | 0.75 | TSHR (0.41) | TSHRL3MBTL1ALDH1A1KMT2AMAPT | |
| Biphenyl SCHEMBL27963687 | 0.75 | TSHR (0.62) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL9323400 | 0.74 | TSHR (0.54) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL11512655 | 0.74 | TSHR (0.52) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032879-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-02-14 | — | — | WO | disclosed |