Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733425 | 0.91 | TSHR (0.53) | LMNAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL446580 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL17555983 | 0.78 | ALDH1A1 (0.49) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL5099862 | 0.78 | TSHR (0.41) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL449722 | 0.75 | LMNA (0.50) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL4905507 | 0.75 | LMNA (0.62) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL28364952 | 0.74 | LMNA (0.49) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL28837354 | 0.73 | SMN1; SMN2 (0.45) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL10690073 | 0.73 | ELANE (0.56) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL4612201 | 0.73 | FFAR1 (0.34) | LMNAALDH1A1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712523-B | Ophthalmic product composition | 爱尔兰眼力健公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115386046-A | Holographic recording medium, holographic high polymer material, preparation method of holographic high polymer material and display device | 华为技术有限公司 | 2022-11-25 | — | — | CN | disclosed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| CN-111712523-A | Ophthalmic product composition | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |