⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218263 | 0.81 | TRPA1 (0.32) | — | |
| SCHEMBL29394860 | 0.81 | TRPA1 (0.32) | — | |
| Quinoxaline SCHEMBL451431 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL7336245 | 0.69 | TRPA1 (0.35) | — | |
| SCHEMBL2863 | 0.67 | — | — | |
| SCHEMBL5712063 | 0.65 | TRPA1 (0.30) | — | |
| SCHEMBL11567982 | 0.63 | IDO1 (0.41) | — | |
| SCHEMBL11567985 | 0.63 | IDO1 (0.41) | — | |
| SCHEMBL379614 | 0.62 | TRPA1 (0.33) | — | |
| SCHEMBL379612 | 0.62 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325497-B1 | QUINSTATIN COMPOUNDS | UNIV ARIZONA STATE (US) | 2020-09-02 | — | — | EP | claimed |
| US-10435435-B2 | Quinstatin compounds | THE ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-08 | — | — | US | claimed |
| US-20180371012-A1 | QUINSTATIN COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-12-27 | — | — | US | claimed |
| EP-3325497-B1 | QUINSTATIN COMPOUNDS | UNIV ARIZONA STATE (US) | 2020-09-02 | — | — | EP | disclosed |
| US-10435435-B2 | Quinstatin compounds | THE ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180371012-A1 | QUINSTATIN COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-12-27 | — | — | US | disclosed |
| EP-3325497-A1 | QUINSTATIN COMPOUNDS | Pettit, George, Robert (US) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017019489-A1 | QUINSTATIN COMPOUNDS | PETTIT GEORGE ROBERT (US) | 2017-02-02 | — | — | WO | disclosed |
| EP-1925611-B1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8088796-B2 | Triamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20110312990-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20060252837-A1 | Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1669350-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20050245565-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1577301-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1577302-A1 | NOVEL ETHYLENEDIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
| US-20050020645-A1 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1405852-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |