SCHEMBL20733706

SCHEMBL20733706

COCc1cc(C)sc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCE Q02156 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MYLK Q15746 2/20 0.34
MEN1 O00255 1/20 0.34
PRKCG P05129 1/20 0.34
MAPT P10636 1/20 0.34
PRKCA P17252 1/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.32
CDK8 P49336 1/20 0.31
CDK19 Q9BWU1 1/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 2/20 0.31
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13337165 0.78 ALDH1A1 (0.36) PRKCEALDH1A1MYLKMEN1PRKCG
SCHEMBL20733707 0.78 PRKCE (0.33) PRKCEALDH1A1MYLKMEN1PRKCG
SCHEMBL12460595 0.76
SCHEMBL12847430 0.74
SCHEMBL13337187 0.69 DPP4 (0.39) PRKCEALDH1A1MYLKMEN1PRKCG
SCHEMBL13337197 0.68 MAPT (0.38) ALDH1A1MAPTRECQLLMNAKDM4E
SCHEMBL13337198 0.68 P2RX3 (0.33) PRKCEALDH1A1MYLKMEN1PRKCG
SCHEMBL25085954 0.67 PRKCE (0.41) PRKCEALDH1A1MYLKMEN1PRKCG
SCHEMBL21737525 0.67
SCHEMBL3356030 0.66 ALDH1A1 (0.48) PRKCEALDH1A1MYLKMEN1PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019030357-A1 PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-02-14 WO disclosed