Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529223 | 0.83 | ABL1 (0.39) | GAAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8630782 | 0.79 | DAO (0.53) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL26281512 | 0.76 | GAA (0.46) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL3661717 | 0.76 | GAA (0.67) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL9429371 | 0.72 | CA1 (0.52) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL937185 | 0.71 | ALDH1A1 (0.71) | GAATSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL8667051 | 0.70 | HDAC3 (0.54) | GAATSHRMAPTALDH1A1RAB9A | |
| SCHEMBL8630776 | 0.69 | GAA (0.49) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL236240 | 0.69 | CYP4F2 (0.57) | GAAMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL18430374 | 0.69 | KDM4E (0.48) | GAAMAPK1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-18 | — | — | US | disclosed |
| EP-3665170-B1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (SE) | 2020-08-06 | — | — | US | disclosed |
| WO-2019030357-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200245624-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | GAA 382/4885MAPK1 4419/4885TSHR 1188/4885 |
| US-20230148600-A1 | PESTICIDALLY ACTIVE THIOPHENE DERIVATIVES | ACHE, DDT, GSTP1 | GAA 321/4885MAPK1 4243/4885TSHR 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.