SCHEMBL236240

SCHEMBL236240

CCOC(=O)c1cc(Cl)c(Cl)cc1C(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.57
CYP4A11 Q02928 1/20 0.57
TSHR P16473 1/20 0.57
BAZ2B Q9UIF8 1/20 0.57
BAZ2A Q9UIF9 1/20 0.57
CA1 P00915 5/20 0.52
CA2 P00918 5/20 0.52
CA12 O43570 4/20 0.52
CA9 Q16790 4/20 0.52
CA7 P43166 3/20 0.52
CA14 Q9ULX7 3/20 0.52
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPK1 P28482 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.48
GLP1R P43220 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15920586 0.92 CYP4F2 (0.51) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL29923060 0.90 CYP4F2 (0.53) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL6732086 0.90 CYP4F2 (0.53) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4625705 0.90 CYP4F2 (0.53) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL10656841 0.88 CA1 (0.59) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4626645 0.88 CYP4F2 (0.51) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4628725 0.88 CYP4F2 (0.48) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4625774 0.88 ALDH1A1 (0.54) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4625822 0.88 ESR1 (0.58) CYP4F2CYP4A11TSHRBAZ2BBAZ2A
SCHEMBL4627261 0.88 CYP4F2 (0.48) CYP4F2CYP4A11TSHRBAZ2BBAZ2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
EP-1283222-B9 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-11-13 EP disclosed
EP-1283222-B2 METHOD FOR PRODUCING A SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2019-03-27 EP disclosed
EP-2636688-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS TOHO TITANIUM CO LTD (JP) 2016-11-16 EP disclosed
CN-103189396-B The manufacture method of solid catalyst component for olefin polymerization, polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2016-06-29 CN disclosed
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
CN-102159596-B Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO LTD 2014-05-07 CN disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
EP-1921092-B1 CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER USING THOSE TOHO TITANIUM CO LTD (JP) 2013-10-02 EP disclosed
EP-2636688-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND OLEFIN POLYMERS Toho Titanium Co., Ltd. (JP) 2013-09-11 EP disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030153454-A1 Solid catalyst ingredient and catalyst each for olefin polymerization and propylene block copolymer TOHO TITANIUM CO., LTD. (JP) 2003-08-14 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1283222-A1 SOLID CATALYST INGREDIENT AND CATALYST EACH FOR OLEFIN POLYMERIZATION AND PROPYLENE BLOCK COPOLYMER Toho Catalyst Co., Ltd. (JP) 2003-02-12 EP disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed
EP-0825178-B1 Phenyl-substituted alkenoylguanidides, process for their preparation, their use as drugs or in diagnostic agents and drugs containing them HOECHST AG (DE) 2001-06-20 EP disclosed
US-6005010-A CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS AND ANTIISCHEMIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
EP-0825178-A1 Phenyl-substituted alkenoylguanidides, process for their preparation, their use as drugs or in diagnostic agents and drugs containing them HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX CYP4F2 220/4885CYP4A11 259/4885TSHR 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.