SCHEMBL20735381

SCHEMBL20735381

O=S(=O)(O)c1cccc(N=Nc2ccc(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 9/20 0.70
PRMT3 O60678 1/20 0.61
EP300 Q09472 1/20 0.61
PRMT6 Q96LA8 1/20 0.61
PRMT1 Q99873 1/20 0.61
PHLPP2 Q6ZVD8 2/20 0.59
CD40 P25942 1/20 0.58
CD40LG P29965 1/20 0.58
NSD2 O96028 1/20 0.52
DUSP3 P51452 1/20 0.52
PTPN5 P54829 1/20 0.52
CASP7 P55210 1/20 0.52
CASP6 P55212 1/20 0.52
PTPN11 Q06124 1/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17515769 0.93 PRMT1 (0.69) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL17540343 0.93 PRMT1 (0.69) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL29538274 0.92 ENPP2 (0.63) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL20736028 0.92 ENPP2 (0.63) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL13350540 0.92 ENPP2 (0.69) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL12757456 0.92 ENPP2 (0.69) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL17545808 0.92 ENPP2 (0.69) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL29538227 0.92 ENPP2 (0.71) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL17518421 0.89 ENPP2 (0.66) ENPP2PRMT3EP300PRMT6PRMT1
SCHEMBL17518451 0.88 CD40 (0.69) ENPP2PRMT3EP300PRMT6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed